"He made us laugh. Hard. Every time you saw him," Crystal said of Williams at the conclusion of a tribute to industry members who died last year. "Robin Williams, what a concept."
Bryan Cranston was honored as best actor in a drama for "Breaking Bad," proving that "True Detective" nominee Matthew McConaughey's movie-star appeal couldn't conquer all.
"I have gratitude for everything that has happened," Cranston said. His victory ties him with four-time best drama actor champ Dennis Franz. Cranston's co-stars Aaron Paula and Anna Gunn were honored in categories for best drama supporting acting,
"Thank you for this wonderful farewell to our show," said "Breaking Bad" creator Vince Gilligan said of the series about a teacher-turned-drug kingpin that ended with a bang.
"The Good Wife" star Julianna Margulies won the Emmy for best lead actress in a drama series. "What a wonderful time for women on television," Margulies said.
McConaughey was the object of too-handsome jokes by presenter Jimmy Kimmel and adoration by winner Gail Mancuso, honored as best director for an episode of "Modern Family."
"If you don't mind, Matthew McConaughey, I'm gonna make eye contact with you right now," she said from the stage, making good by holding the actor's gaze for much of her speech.
The ceremony honoring the best of TV wasn't shy about playing the movie-star card. "Six minutes to Woody Harrelson" flashed on screen during Colin Bucksey's acceptance speech for best miniseries direction for "Fargo."
Harrelson and his "True Detective" co-star were given time to banter before announcing that Benedict Cumberbatch of "Sherlock: His Last Vow" was the winner of the best miniseries actor award.
"So you won Oscar, (People magazine's) Sexiest Man Alive and now you want an Emmy, too. Isn't that a little bit greedy?" Harrelson teased his fellow nominee.
"Fargo" was named best miniseries, and the award for best miniseries actress went to Jessica Lange of "American Horror Story: Coven."
Buffering the miniseries awards was a parody routine about top nominees by "Weird Al" Yankovic. Musical numbers usually look out of place at the Emmys, and this one was no different. Other scripted banter fell flat, although host Seth Meyers kept soldiering on.
CBS' "The Big Bang Theory" star Jim Parsons was crowned as best comedy series actor, giving him his fourth Emmy and putting him in league with all-time sitcom winners Kelsey Grammer and Michael J. Fox.
ABC's "Modern Family," which tied "Frasier" as the all-time sitcom champ with five statuettes, also captured a best comedy supporting actor trophy for Ty Burrell. Allison Janney was honored as best supporting comedy actress for CBS' "Mom," adding to the trophy she'd already picked up as guest actress on "Masters of Sex."
Julia Louis-Dreyfus, who received her third consecutive best comedy actress Emmy for the political comedy "Veep," drew big laughs as she stopped to exchange faux heated kisses with Cranston, who earlier was her co-presenter and who appeared with her on "Seinfeld."
Meyers kicked off the ceremony by tweaking his home network, NBC, and other broadcasters for being eclipsed in the awards by cable series and online newcomers like "Orange Is the New Black."
Noting that the Emmys moved to Monday night to avoid a conflict with Sunday's MTV Video Music Awards, he said that MTV doesn't really specialize in videos anymore.
"That's like network TV holding an awards show and giving all the trophies to cable and Netflix. That would be crazy," Meyers joked.
The ceremony's traditional "in memorian" tribute to industry members who have died in the past year flashed images of stars including James Garner, Ruby Dee, Sid Caesar, Carmen Zapata and Elaine Stritch as singer-songwriter Sara Bareilles sang "Smile." It concluded with the tribute to Williams.